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RWJ 50271

RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).

Catalog No. T12783Cas No. 162112-37-0

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Purity:99.09%

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RWJ 50271

Catalog No. T12783Cas No. 162112-37-0

RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$159	In Stock
5 mg	$392	In Stock
10 mg	$587	In Stock
25 mg	$922	In Stock
50 mg	$1,230	In Stock
100 mg	$1,670	In Stock
1 mL x 10 mM (in DMSO)	$443	In Stock

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Product Introduction

Bioactivity

Description	RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
Targets&IC50	LFA1-ICAM1 (HL60 cells):5.0 μM

Chemical Properties

Molecular Weight	410.41
Formula	C₁₈H₁₇F₃N₄O₂S
Cas No.	162112-37-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 230 mg/mL (487.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4366 mL	12.1829 mL	24.3659 mL	121.8294 mL
5 mM	0.4873 mL	2.4366 mL	4.8732 mL	24.3659 mL
10 mM	0.2437 mL	1.2183 mL	2.4366 mL	12.1829 mL
20 mM	0.1218 mL	0.6091 mL	1.2183 mL	6.0915 mL
50 mM	0.0487 mL	0.2437 mL	0.4873 mL	2.4366 mL
100 mM	0.0244 mL	0.1218 mL	0.2437 mL	1.2183 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc